PGBD3 antibody (N-Term)

Catalog No. ABIN2775267

There is 1 publication for this product available. The Rabbit Polyclonal anti-PGBD3 antibody is suitable to detect PGBD3 in samples from Human. It has been validated for WB.

Quick Overview for PGBD3 antibody (N-Term) (ABIN2775267)

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGBD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PGBD3 Antibody

Binding Specificity: N-Term

Sequence: AESDSDDPSY APKDDSPDEV PSTFTVQQPP PSRRRKMTKI LCKWKKADLT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PGBD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PGBD3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 593 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PGBD3 antibody (ABIN2775267)

Newman, Bailey, Fan, Pavelitz, Weiner: "An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome." in: PLoS genetics, Vol. 4, Issue 3, pp. e1000031, (2008) (PubMed).

Target Details for PGBD3

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Alternative Name: PGBD3

Background: The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. Anti-PGBD3 belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. Anti-PGBD3 overlaps with the ERCC6 gene on chromosome 10, and pseudogenes of this locus have been found on chromosomes 4, 5 and 12. The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene overlaps with the ERCC6 gene on chromosome 10, and pseudogenes of this locus have been found on chromosomes 4, 5 and 12.
Alias Symbols: FLJ90201
Protein Interaction Partner: HOXA11,
Protein Size: 593

Molecular Weight: 67 kDa

Gene ID: 267004

NCBI Accession: NM_170753, NP_736609

UniProt: Q8N328

Pathways: Chromatin Binding