IGFALS antibody (Middle Region)

Catalog No. ABIN2775292

This Rabbit Polyclonal antibody specifically detects IGFALS in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow and Dog.

Quick Overview for IGFALS antibody (Middle Region) (ABIN2775292)

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFALS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IGFALS Antibody

Binding Specificity: Middle Region

Sequence: PGLLGLRVLR LSHNAIASLR PRTFKDLHFL EELQLGHNRI RQLAERSFEG

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against IGFALS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IGFALS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 605 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGFALS

Target: IGFALS (Insulin-Like Growth Factor Binding Protein, Acid Labile Subunit (IGFALS))

Alternative Name: IGFALS

Background: IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in IGFALS are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Alias Symbols: ALS
Protein Interaction Partner: PDCD6, IGF1, IGFBP5, IGFBP3,
Protein Size: 605

Molecular Weight: 63 kDa

Gene ID: 3483

NCBI Accession: NM_004970, NP_004961

UniProt: P35858