GEM antibody (C-Term)

Catalog No. ABIN2775304

The Rabbit Polyclonal anti-GEM antibody has been validated for WB and IHC. It is suitable to detect GEM in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for GEM antibody (C-Term) (ABIN2775304)

Target: GEM (GTP Binding Protein Overexpressed in Skeletal Muscle (GEM))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GEM Antibody

Binding Specificity: C-Term

Sequence: ETSAAVQHNV KELFEGIVRQ VRLRRDSKEK NERRLAYQKR KESMPRKARR FW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GEM. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GEM

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 296 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GEM

Target: GEM (GTP Binding Protein Overexpressed in Skeletal Muscle (GEM))

Alternative Name: GEM

Background: GEM belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction.The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Alias Symbols: KIR, MGC26294
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-7, INO80E, CCDC67, KLC3, KRT40, SSX2IP, LZTS2, COG8, CCDC102B, TRIM54, KCTD9, TFIP11, IKZF3, RUNDC3A, AHCYL1, PNMA1, BLZF1, TRAF1, TCF4, TRIM27, KRT31, GOLGA2, TRIM23, CLDN15, CLEC4G, YBEY, NDUFAF3, RNF7, VTN, SDHB, NDUFS8, CT
Protein Size: 296

Molecular Weight: 33 kDa

Gene ID: 2669

NCBI Accession: NM_005261, NP_005252

UniProt: P55040