GPR6 antibody (N-Term)

Catalog No. ABIN405451

This Rabbit Polyclonal antibody specifically detects GPR6 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for GPR6 antibody (N-Term) (ABIN405451)

Target: GPR6 (G Protein-Coupled Receptor 6 (GPR6))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GPR6 Antibody

Binding Specificity: N-Term

Purpose: GPR6 Antibody - N-terminal region

Sequence: NASAASLNDS QVVVVAAEGA AAAATAAGGP DTGEWGPPAA AALGAGGGAN

Predicted Reactivity: Cow: 86%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GPR6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPR6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42229-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR6

Target: GPR6 (G Protein-Coupled Receptor 6 (GPR6))

Alternative Name: GPR6

Background:

Background Information: GPR6 belongs to the G-protein coupled receptor 1 family.It is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Gene Name: G protein-coupled receptor 6

Alternative Symbols: -

Protein Name: G-protein coupled receptor 6

Molecular Weight: 38kDa

Gene ID: 2830

NCBI Accession: NP_005275

UniProt: P46095