PSCA antibody (C-Term)

Catalog No. ABIN2775319

This Rabbit Polyclonal antibody specifically detects PSCA in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog and Guinea Pig.

Quick Overview for PSCA antibody (C-Term) (ABIN2775319)

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSCA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSCA Antibody

Binding Specificity: C-Term

Purpose: PSCA Antibody - C-terminal region

Sequence: TVISKGCSLN CVDDSQDYYV GKKNITCCDT DLCNASGAHA LQPAAAILAL

Predicted Reactivity: Dog: 86%, Guinea Pig: 79%, Human: 100%, Mouse: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against PSCA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSCA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42250-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSCA

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Alternative Name: PSCA

Background:

Background Information: This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

Gene Name: Prostate stem cell antigen

Alternative Symbols: PRO232

Protein Name: Prostate stem cell antigen

Molecular Weight: 13kDa

Gene ID: 8000

NCBI Accession: NP_005663

UniProt: O43653