AGR2 antibody (Middle Region)

Catalog No. ABIN2775338

Product Details anti-AGR2 Antibody

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against AGR2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AGR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 175 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AGR2

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Alternative Name: AGR2 (AGR2 Products)

Synonyms: AG2 antibody, GOB-4 antibody, HAG-2 antibody, PDIA17 antibody, XAG-2 antibody, Agr2h antibody, Gob-4 antibody, mAG-2 antibody, wu:fj29g05 antibody, zgc:112187 antibody, agr2 antibody, hag3 antibody, hag-3 antibody, bcmp11 antibody, MGC89004 antibody, XAgr2 antibody, agr2-A antibody, anterior gradient 2, protein disulphide isomerase family member antibody, anterior gradient 2 antibody, anterior gradient 3, protein disulphide isomerase family member antibody, anterior gradient 2, protein disulphide isomerase family member S homeolog antibody, AGR2 antibody, Agr2 antibody, agr2 antibody, agr3 antibody, agr2.S antibody

Background: AGR2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Increased AGR2 expression is a valuable prognostic factor to predict the clinical outcome of the prostate cancer patients.
Alias Symbols: AG2, GOB-4, HAG-2, XAG-2, PDIA17
Protein Interaction Partner: UBQLN1, HUWE1, POM121, KRT31, FABP2, CATSPER1, NUP62CL, ATP4A, NPM1, NOS2, MLH1, APP, UBQLN4, LYPD3, DAG1, POU5F1, MED31, CCDC90B, BRD7, CRMP1,
Protein Size: 175

Molecular Weight: 20 kDa

Gene ID: 10551

NCBI Accession: NM_006408, NP_006399

UniProt: O95994