PPP1R1A antibody (N-Term)

Catalog No. ABIN2775347

This Rabbit Polyclonal antibody specifically detects PPP1R1A in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Guinea Pig and Rabbit.

Quick Overview for PPP1R1A antibody (N-Term) (ABIN2775347)

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP1R1A Antibody

Binding Specificity: N-Term

Purpose: Ppp1r1a Antibody - N-terminal region

Sequence: FTVPLLEPHL DPEAAEQIRR RRPTPATLVL TSDQSSPEID EDRIPNSLLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Ppp1r1a. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42314-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP1R1A

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Alternative Name: Ppp1r1a

Background:

Targeted Subunit: 1A

Background Information: Ppp1r1a is an inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Gene Name: Protein phosphatase 1, regulatory (inhibitor) subunit 1A

Alternative Symbols: I-, I-1, inhib, 0610038N18Rik

Protein Name: Protein phosphatase 1 regulatory subunit 1A

Molecular Weight: 19kDa

Gene ID: 58200

NCBI Accession: NP_067366

UniProt: Q9ERT9

Pathways: Cellular Glucan Metabolic Process