SARDH antibody (C-Term)

Catalog No. ABIN2775362

This anti-SARDH antibody is a Rabbit Polyclonal antibody detecting SARDH in WB. Suitable for Mouse, Human, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Pig and Rabbit.

Quick Overview for SARDH antibody (C-Term) (ABIN2775362)

Target: SARDH (Sarcosine Dehydrogenase (SARDH))

Reactivity: Mouse, Human, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARDH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SARDH Antibody

Binding Specificity: C-Term

Sequence: SLSIEKGYRH WHADLRPDDS PLEAGLAFTC KLKSPVPFLG REALEQQRAA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against SARDH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SARDH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SARDH

Target: SARDH (Sarcosine Dehydrogenase (SARDH))

Alternative Name: SARDH

Background: This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described.
Alias Symbols: SAR, SDH, SARD, BPR-2, DMGDHL1
Protein Size: 368

Molecular Weight: 40 kDa

Gene ID: 1757

NCBI Accession: NM_001134707, NP_001128179

UniProt: Q9UL12