GPR161 antibody (Middle Region)

Catalog No. ABIN2775370

The Rabbit Polyclonal anti-GPR161 antibody (ABIN2775370) specifically detects GPR161 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse and Rabbit samples.

Quick Overview for GPR161 antibody (Middle Region) (ABIN2775370)

Target: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR161 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPR161 Antibody

Binding Specificity: Middle Region

Purpose: GPR161 Antibody - middle region

Sequence: SISNRITDLG LSPHLTALMA GGQPLGHSSS TGDTGFSCSQ DSGTDMMLLE

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GPR161. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GPR161

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42355-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GPR161

Target: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Alternative Name: GPR161

Background:

Background Information: Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling.

Gene Name: G protein-coupled receptor 161

Alternative Symbols: RE2

Protein Name: G-protein coupled receptor 161

Molecular Weight: 58kDa

Gene ID: 23432

NCBI Accession: NP_722561

UniProt: Q8N6U8

Pathways: cAMP Metabolic Process