Myosin XVI antibody (Middle Region)

Catalog No. ABIN2775412

The Rabbit Polyclonal anti-Myosin XVI antibody is suitable to detect Myosin XVI in samples from Human, Mouse, Rat, Cow, Dog, Horse, Pig and Guinea Pig. It has been validated for WB.

Quick Overview for Myosin XVI antibody (Middle Region) (ABIN2775412)

Target: Myosin XVI (MYO16)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin XVI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Myosin XVI Antibody

Binding Specificity: Middle Region

Purpose: MYO16 Antibody - middle region

Sequence: PPHLFSCVER AFHQLFREQR PQCFILSGER GSGKSEASKQ IIRHLTCRAG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against MYO16. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MYO16

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42427-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Myosin XVI

Target: Myosin XVI (MYO16)

Alternative Name: MYO16

Background:

Background Information: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO16 may be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. It activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis.

Gene Name: myosin XVI

Alternative Symbols: MYR8, MYAP3, NYAP3, Myo16b, PPP1R107

Protein Name: Unconventional myosin-XVI

Molecular Weight: 80kDa

Gene ID: 23026

UniProt: Q9Y6X6