BMP2K antibody (Middle Region)

Catalog No. ABIN2775439

This Rabbit Polyclonal antibody specifically detects BMP2K in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for BMP2K antibody (Middle Region) (ABIN2775439)

Target: BMP2K (BMP2 Inducible Kinase (BMP2K))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP2K antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BMP2K Antibody

Binding Specificity: Middle Region

Purpose: BMP2K Antibody - middle region

Sequence: VKVLAPGEFG NHRPKGALRP GNGPEILLGQ GPPQQPPQQH RVLQQLQQGD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 83%, Human: 100%, Mouse: 100%, Rat: 92%, Yeast: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against BMP2K. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BMP2K

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42482-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for BMP2K

Target: BMP2K (BMP2 Inducible Kinase (BMP2K))

Alternative Name: BMP2K

Background:

Background Information: BMP2K is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. BMP2K is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: BMP2 inducible kinase

Alternative Symbols: BIKE, HRIHFB2017

Protein Name: Putative uncharacterized protein BMP2K EMBL AAY40926.1

Molecular Weight: 74kDa

Gene ID: 55589

NCBI Accession: NP_060063

UniProt: Q4W5H2