BMP2K antibody (C-Term)
Quick Overview for BMP2K antibody (C-Term) (ABIN2775440)
Target
See all BMP2K AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- AQHQPSQQQA SPEYLTSPQE FSPALVSYTS SLPAQVGTIM DSSYSANRSV
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against BMP2K. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human BMP2K
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 662 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BMP2K (BMP2 Inducible Kinase (BMP2K))
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Alternative Name
- BMP2K
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Background
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BMP2K is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. BMP2K is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BIKE, DKFZp434K0614, DKFZp434P0116, HRIHFB2017
Protein Interaction Partner: FN1, EPS15, AP2M1, ABL1, TERF2, TERF1, KDM5B, MBP,
Protein Size: 662 -
Molecular Weight
- 74 kDa
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Gene ID
- 55589
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NCBI Accession
- NM_017593, NP_060063
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UniProt
- Q4W5H2
Target
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