AKR1B10 antibody (N-Term)

Catalog No. ABIN2775474

Cited in 1 publication. The Rabbit Polyclonal anti-AKR1B10 antibody (ABIN2775474) specifically detects AKR1B10 in WB. The antibody is reactive with Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit and Saccharomyces cerevisiae samples.

Quick Overview for AKR1B10 antibody (N-Term) (ABIN2775474)

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1B10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AKR1B10 Antibody

Binding Specificity: N-Term

Purpose: AKR1B10 Antibody - N-terminal region

Sequence: NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against AKR1B10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B10

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8094405

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-AKR1B10 antibody (ABIN2775474)

Cheng, Zhang, Kotani, Watanabe, Lee, Wang, Kawashima, Tai, Taniguchi, Honke: "Production of a recombinant single-chain variable-fragment (scFv) antibody against sulfoglycolipid." in: Journal of biochemistry, Vol. 137, Issue 3, pp. 415-21, (2005) (PubMed).

Target Details for AKR1B10

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Alternative Name: AKR1B10

Background:

Background Information: AKR1B10 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.

Gene Name: Aldo-keto reductase family 1, member B10 (aldose reductase)

Alternative Symbols: HIS, HSI, ARL1, ARL-1, ALDRLn, AKR1B11, AKR1B12

Protein Name: Aldo-keto reductase family 1 member B10

Molecular Weight: 35kDa

Gene ID: 57016

NCBI Accession: NP_064695

UniProt: O60218