PAPPA2 antibody (N-Term)

Catalog No. ABIN2775475

The Rabbit Polyclonal anti-PAPPA2 antibody (ABIN2775475) specifically detects PAPPA2 in WB. The antibody is reactive with Human, Rat and Guinea Pig samples.

Quick Overview for PAPPA2 antibody (N-Term) (ABIN2775475)

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPPA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAPPA2 Antibody

Binding Specificity: N-Term

Purpose: PAPPA2 Antibody - N-terminal region

Sequence: PPDLTENPAG LRGAVEEPAA PWVGDSPIGQ SELLGDDDAY LGNQRSKESL

Predicted Reactivity: Guinea Pig: 85%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PAPPA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAPPA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42555-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAPPA2

Target: PAPPA2 (Pappalysin 2 (PAPPA2))

Alternative Name: PAPPA2

Background:

Background Information: PAPPA2 is a metalloproteinase which specifically cleaves IGFBP-5. It shows limited proteolysis toward IGFBP-3.

Gene Name: Pappalysin 2

Alternative Symbols: PAPPE, PLAC3, PAPP-E, PAPP-A2

Protein Name: Pappalysin-2

Molecular Weight: 92kDa

Gene ID: 60676

NCBI Accession: NP_068755

UniProt: A9Z1Y8