ELMO3 antibody (Middle Region)

Catalog No. ABIN2775507

The Rabbit Polyclonal anti-ELMO3 antibody is suitable to detect ELMO3 in samples from Human, Mouse, Rat, Horse, Dog, Cow, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for ELMO3 antibody (Middle Region) (ABIN2775507)

Target: ELMO3 (Engulfment and Cell Motility 3 (ELMO3))

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELMO3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ELMO3 Antibody

Binding Specificity: Middle Region

Purpose: ELMO3 Antibody - middle region

Sequence: RKLGFSNSNP AQDLERVPPG LLALDNMLYF SRNAPSAYSR FVLENSSRED

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ELMO3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELMO3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42635-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELMO3

Target: ELMO3 (Engulfment and Cell Motility 3 (ELMO3))

Alternative Name: ELMO3

Background:

Background Information: ELMO3 is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.

Gene Name: Engulfment and cell motility 3

Alternative Symbols: CED12, CED-12, ELMO-3

Protein Name: Engulfment and cell motility protein 3

Molecular Weight: 87kDa

Gene ID: 79767

NCBI Accession: NP_078988

UniProt: Q96BJ8