GAMT antibody (Middle Region)

Catalog No. ABIN2775546

There is 1 publication for this product available. The Rabbit Polyclonal anti-GAMT antibody is suitable to detect GAMT in samples from Human. It has been validated for WB and IHC.

Quick Overview for GAMT antibody (Middle Region) (ABIN2775546)

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAMT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GAMT Antibody

Binding Specificity: Middle Region

Purpose: GAMT Antibody - middle region

Sequence: PGEGPFLTPW VGWTVLVHLE IKVLCLAQWL PGAVAQVYNP STVEGRGGQI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GAMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GAMT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42700-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-GAMT antibody (ABIN2775546)

Borini, Staiano, Rocchia, Rossi, Rossi, DAuria: "Advanced nanotechnological approaches for designing protein-based "lab-on-chips" sensors on porous silicon wafer." in: Recent patents on DNA & gene sequences, Vol. 1, Issue 1, pp. 1-7, (2008) (PubMed).

Target Details for GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: GAMT

Background:

Background Information: GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumula

Gene Name: Guanidinoacetate N-methyltransferase

Alternative Symbols: PIG2, CCDS2, TP53I2, HEL-S-20

Protein Name: Guanidinoacetate N-methyltransferase

Molecular Weight: 29kDa

Gene ID: 2593

NCBI Accession: NP_620279

UniProt: A8K0A0