PLPP1 (N-Term) antibody

Catalog No. ABIN310386

Cited in 1 publication. The Rabbit Polyclonal anti-PLPP1 antibody (ABIN310386) specifically detects PLPP1 in IHC and WB. The antibody is reactive with Human, Mouse, Rat and Guinea Pig samples.

Quick Overview for PLPP1 (N-Term) antibody (ABIN310386)

Target: PLPP1

Reactivity: Human, Mouse, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: PLPP1 Antibody - N-terminal region

Sequence: QIYPFQRGFF CKDNSINYPY HDSTVTSTVL ILVGVGLPIS SIILGETLSV

Predicted Reactivity: Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PPAP2A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPAP2A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108398

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References

Evseenko, Latour, Richardson, Corselli, Sahaghian, Cardinal, Zhu, Chan, Dunn, Crooks: "Lysophosphatidic acid mediates myeloid differentiation within the human bone marrow microenvironment." in: PLoS ONE, Vol. 8, Issue 5, pp. e63718, (2013) (PubMed).

Target Details

Target: PLPP1

Background:

Background Information: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in synthesis of glycerolipids and in phospholipase D-mediated signal transduction. This enzyme is an integral membrane glycoprotein that plays a role in the hydrolysis and uptake of lipids from extracellular space. Alternate splicing results in multiple transcript variants of this gene.

Gene Name: phospholipid phosphatase 1

Alternative Symbols: LPP1, PAP2, LLP1a, PAP-2a, PPAP2A

Protein Name: phospholipid phosphatase 1

Molecular Weight: 31kDa

Gene ID: 8611

NCBI Accession: NP_795714

UniProt: O14494