RGS2 antibody (Middle Region)

Catalog No. ABIN2775595

This Rabbit Polyclonal antibody specifically detects RGS2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit and Sheep.

Quick Overview for RGS2 antibody (Middle Region) (ABIN2775595)

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS2 Antibody

Binding Specificity: Middle Region

Purpose: Rgs2 Antibody - middle region

Sequence: LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against Rgs2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse Rgs2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42827-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS2

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Alternative Name: Rgs2

Background:

Background Information: Rgs2 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It may play a role in leukemogenesis.

Gene Name: Regulator of G-protein signaling 2

Alternative Symbols: GO, GOS8

Protein Name: Regulator of G-protein signaling 2

Molecular Weight: 23kDa

Gene ID: 19735

NCBI Accession: NP_033087

UniProt: O08849

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation