NR2F1 antibody (N-Term)
Quick Overview for NR2F1 antibody (N-Term) (ABIN2775597)
Target
See all NR2F1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- YCRLKKCLKV GMRREAVQRG RMPPTQPNPG QYALTNGDPL NGHCYLSGYI
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Predicted Reactivity
- Cow: 100%, Dog: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Sheep: 79%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against NR2F1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of human NR2F1
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NR2F1 (Nuclear Receptor Subfamily 2, Group F, Member 1 (NR2F1))
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Alternative Name
- NR2F1
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Background
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The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS).
Alias Symbols: EAR3, BBOAS, EAR-3, NR2F2, SVP44, BBSOAS, ERBAL3, TFCOUP1, COUP-TFI, TCFCOUP1
Protein Size: 372 -
Molecular Weight
- 40 kDa
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Gene ID
- 7025
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NCBI Accession
- NM_005654, NP_005645
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UniProt
- P10589
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Target
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