RGS7 antibody (N-Term)

Catalog No. ABIN2775599

The Rabbit Polyclonal anti-RGS7 antibody has been validated for WB. It is suitable to detect RGS7 in samples from Human, Mouse, Rat and Cow.

Quick Overview for RGS7 antibody (N-Term) (ABIN2775599)

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS7 Antibody

Binding Specificity: N-Term

Sequence: MAQGNNYGQT SNGVADESPN MLVYRKMEDV IARMQDEKNG IPIRTVKSFL

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Rgs7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Rgs7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 469 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS7

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Alternative Name: Rgs7

Background: Rgs7 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. It may play an important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations and in synaptic vesicle exocytosis
Protein Interaction Partner: Rgs7bp,
Protein Size: 469

Molecular Weight: 52 kDa

Gene ID: 24012

NCBI Accession: NM_011880, NP_036010

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling