RGS7 antibody (C-Term)

Catalog No. ABIN655954

This Rabbit Polyclonal antibody specifically detects RGS7 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RGS7 antibody (C-Term) (ABIN655954)

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31661

Product Details anti-RGS7 Antibody

Binding Specificity: AA 440-469, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human RGS7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for RGS7

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Alternative Name: RGS7

Background: RGS7 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations (By similarity).

Molecular Weight: 57668

Gene ID: 6000

NCBI Accession: NP_002915

UniProt: P49802

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling