RGS7 antibody

Catalog No. ABIN2856096

Product Details anti-RGS7 Antibody

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS7 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to RGS7 (regulator of G-protein signaling 7)
RGS7 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RGS7. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG , SK-N-SH

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RGS7

Target: RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

Alternative Name: regulator of G protein signaling 7 (RGS7 Products)

Synonyms: zgc:92793 antibody, RGS7 antibody, regulator of G-protein signaling 7 antibody, regulator of G protein signaling 7a antibody, regulator of G protein signaling 7 antibody, Regulator of G protein Signaling antibody, RGS7 antibody, rgs7a antibody, CpipJ_CPIJ014798 antibody, Tsp_03415 antibody, rgs-7 antibody, Rgs7 antibody

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations.

Molecular Weight: 58 kDa

Gene ID: 6000

UniProt: P49802

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling