Tricellulin antibody (Middle Region)

Catalog No. ABIN2775617

This Rabbit Polyclonal antibody specifically detects Tricellulin in WB. It exhibits reactivity toward Human, Rat, Mouse, Pig, Cow, Dog, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Tricellulin antibody (Middle Region) (ABIN2775617)

Target: Tricellulin (MARVELD2)

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tricellulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tricellulin Antibody

Binding Specificity: Middle Region

Sequence: PKTPFVLVVA GLAWITTIII LVLGMSMYYR TILLDSNWWP LTEFGINVAL

Predicted Reactivity: Cow: 100%, Dog: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MARVELD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MARVELD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 457 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tricellulin

Target: Tricellulin (MARVELD2)

Alternative Name: MARVELD2

Background: Tight junctions (TJ) prevent leakage of solutes through the paracellular pathway of epithelial cells. MARVELD2, or tricellulin (TRIC), is an integral membrane protein concentrated at the vertically oriented TJ strands of tricellular contacts (Ikenouchi et
Alias Symbols: DFNB49, FLJ30532, MARVD2, MRVLDC2, Tric
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 457

Molecular Weight: 52 kDa

Gene ID: 153562

NCBI Accession: NM_144724, NP_653325

UniProt: C9J8H4

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization