PATJ antibody (N-Term)

Catalog No. ABIN2775641

Product Details anti-PATJ Antibody

Target: PATJ (INADL) (InaD-Like (INADL))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow, Dog, Rabbit, Guinea Pig, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PATJ antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EVMVATLDTQ IADDAELQKY SKLLPIHTLR LGVEVDSFDG HHYISSIVSG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against INADL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human INADL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1801 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PATJ antibody (ABIN2775641)

Storrs, Silverstein: "PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6." in: Journal of virology, Vol. 81, Issue 8, pp. 4080-90, (2007) (PubMed).

Target Details for PATJ

Target: PATJ (INADL) (InaD-Like (INADL))

Alternative Name: INADL (INADL Products)

Synonyms: wu:fc76h08 antibody, si:dz129i22.4 antibody, si:busm1-129i22.4 antibody, Cipp antibody, InaD-like antibody, PATJ antibody, hINADL antibody, Patj antibody, Inadl2 antibody, RGD1565362 antibody, PATJ, crumbs cell polarity complex component antibody, patj antibody, PATJ antibody, Patj antibody

Background: INADL is a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Cipp, FLJ26982, PATJ, hINADL, InaD-like
Protein Interaction Partner: SUMO1, UBC, NEDD8, AMOT, SAV1, AMOTL2, LATS2, YAP1, LATS1, Wwtr1, BAI1, TP53RK, PARD3, Dlg4, ARHGAP17, SUMO2, TJP3, CRB3, PRDM16, NRXN2, ASIC3, MPP5, NLGN2, CNKSR2, PAX6, GLS2, DDX18, KIF1B, CRIPT, SCN4A, CLDN1, CACNG2, GRIN2D, MAPK12, KCNJ10, KCNJ15, KCN
Protein Size: 1801

Molecular Weight: 196 kDa

Gene ID: 10207

NCBI Accession: NM_176877, NP_795352

UniProt: Q8NI35