TRIM72 antibody (Middle Region)

Catalog No. ABIN2775659

Product Details anti-TRIM72 Antibody

Target: TRIM72 (Tripartite Motif Containing 72 (TRIM72))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM72 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LEELTFDPSS AHPSLVVSSS GRRVECSEQK APPAGEDPRQ FDKAVAVVAH

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM72. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM72

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 477 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRIM72 antibody (ABIN2775659)

Lemckert, Bournazos, Eckert, Kenzler, Hawkes, Butler, Ceely, North, Winlaw, Egan, Cooper: "Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor." in: Cardiovascular research, Vol. 110, Issue 2, pp. 178-87, (2016) (PubMed).

Target Details for TRIM72

Target: TRIM72 (Tripartite Motif Containing 72 (TRIM72))

Alternative Name: TRIM72 (TRIM72 Products)

Background: TRIM72 belongs to the TRIM/RBCC family. It contains 1 B box-type zinc finger and 1 B30.2/SPRY domain and 1 RING-type zinc finger. The function of TRIM72 remains unknown.
Alias Symbols: MG53
Protein Interaction Partner: TCF12, PTK2, UBE2N, UBE2H, PTRF, MYH9, UBE2I,
Protein Size: 477

Molecular Weight: 53 kDa

Gene ID: 493829

NCBI Accession: NM_001008274, NP_001008275

UniProt: Q6ZMU5