FKBP6 antibody (Middle Region)

Catalog No. ABIN2775685

The Rabbit Polyclonal anti-FKBP6 antibody is suitable to detect FKBP6 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for FKBP6 antibody (Middle Region) (ABIN2775685)

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FKBP6 Antibody

Binding Specificity: Middle Region

Purpose: FKBP6 Antibody - middle region

Sequence: FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FKBP6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FKBP6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100744

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP6

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Alternative Name: FKBP6

Background:

Background Information: FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Gene Name: FK506 binding protein 6, 36 kDa

Alternative Symbols: FKBP36

Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP6

Molecular Weight: 53kDa

Gene ID: 8468

NCBI Accession: NP_003593

UniProt: O75344

Pathways: M Phase