COLQ antibody (N-Term)

Catalog No. ABIN2775748

Product Details anti-COLQ Antibody

Target: COLQ (AChE Q Subunit (COLQ))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLQ antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LQLFFLSIVS QPTFINSVLP ISAALPSLDQ KKRGGHKACC LLTPPPPPLF

Predicted Reactivity: Cow: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against COLQ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COLQ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 455 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COLQ

Target: COLQ (AChE Q Subunit (COLQ))

Alternative Name: COLQ (COLQ Products)

Synonyms: EAD antibody, A130034K24Rik antibody, collagen like tail subunit of asymmetric acetylcholinesterase antibody, collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase antibody, COLQ antibody, Colq antibody

Background: COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.
Alias Symbols: EAD
Protein Interaction Partner: UBC, MUSK, BCHE, ACHE,
Protein Size: 455

Molecular Weight: 48 kDa

Gene ID: 8292

NCBI Accession: NM_005677, NP_005668

UniProt: Q6DK18