CHD1 antibody (Middle Region)

Catalog No. ABIN2775751

This Rabbit Polyclonal antibody specifically detects CHD1 in WB. It exhibits reactivity toward Human, Mouse, Horse, Rabbit, Dog and Guinea Pig.

Quick Overview for CHD1 antibody (Middle Region) (ABIN2775751)

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Reactivity: Human, Mouse, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHD1 Antibody

Binding Specificity: Middle Region

Sequence: RRKARAKKNK AMKSIKVKEE IKSDSSPLPS EKSDEDDDKL SESKSDGRER

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against CHD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1710 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Alternative Name: CHD1

Background: The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access
Alias Symbols: DKFZp686E2337
Protein Interaction Partner: FBXW11, UBC, ISG15, SPP1, SIRT7, ELAVL1, PAF1, SUMO2, SUMO1, MLLT1, HIST1H3A, CEBPA, HMGA1, SSRP1, SRSF3, SAFB, HIST3H3, HDAC1, H3F3B, NCOR1, BCLAF1, ARRB1,
Protein Size: 1710

Molecular Weight: 197 kDa

Gene ID: 1105

NCBI Accession: NM_001270, NP_001261

UniProt: O14646

Pathways: Chromatin Binding