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CBX1 antibody (N-Term)

CBX1 Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775787
  • Target See all CBX1 Antibodies
    CBX1 (Chromobox Homolog 1 (CBX1))
    Binding Specificity
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 46
    • 19
    • 15
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
    Host
    • 35
    • 9
    • 1
    • 1
    Rabbit
    Clonality
    • 35
    • 10
    • 1
    Polyclonal
    Conjugate
    • 28
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CBX1 antibody is un-conjugated
    Application
    • 35
    • 25
    • 9
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1
    Top Product
    Discover our top product CBX1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 185 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ayoub, Jeyasekharan, Bernal, Venkitaraman: "HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).

  • Target
    CBX1 (Chromobox Homolog 1 (CBX1))
    Alternative Name
    CBX1 (CBX1 Products)
    Synonyms
    CBX antibody, HP1-BETA antibody, HP1Hs-beta antibody, HP1Hsbeta antibody, M31 antibody, MOD1 antibody, p25beta antibody, Cbx antibody, Cbx-rs2 antibody, E430007M08Rik antibody, HP1B antibody, Hp1beta antibody, cbx1 antibody, wu:fe14b09 antibody, zgc:55739 antibody, zgc:86924 antibody, chromobox 1 antibody, chromobox homolog 1a (HP1 beta homolog Drosophila) antibody, chromobox 1 S homeolog antibody, chromobox homolog 1b (HP1 beta homolog Drosophila) antibody, CBX1 antibody, Cbx1 antibody, cbx1a antibody, cbx1.S antibody, cbx1b antibody
    Background
    CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in
    Alias Symbols: CBX, HP1-BETA, HP1Hs-beta, M31, MOD1, p25beta, HP1Hsbeta
    Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
    Protein Size: 185
    Molecular Weight
    21 kDa
    Gene ID
    10951
    NCBI Accession
    NM_006807, NP_006798
    UniProt
    P83916
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