CHMP3 antibody (N-Term)

Catalog No. ABIN2775802

The Rabbit Polyclonal anti-CHMP3 antibody (ABIN2775802) specifically detects CHMP3 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for CHMP3 antibody (N-Term) (ABIN2775802)

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHMP3 Antibody

Binding Specificity: N-Term

Sequence: RVVDRQIRDI QREEEKVKRS VKDAAKKGQK DVCIVLAKEM IRSRKAVSKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against VPS24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VPS24

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 222 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHMP3

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Alternative Name: VPS24

Background: VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.
Alias Symbols: NEDF, VPS24, CGI-149
Protein Interaction Partner: STAMBP, SMAD5, SMAD1, ATP6V1B1, APP, UBD, CHMP4B, CHMP3, CHMP2A, CHMP2B, TNPO3, RAB11A, CHMP4A, VAV2, UBC, VTA1, VPS4A, IGFBP7,
Protein Size: 222

Molecular Weight: 25 kDa

Gene ID: 51652

NCBI Accession: NM_016079, NP_057163

UniProt: Q3ZTS9