CAND1 antibody (N-Term)

Catalog No. ABIN2775888

The Rabbit Polyclonal anti-CAND1 antibody (ABIN2775888) specifically detects CAND1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for CAND1 antibody (N-Term) (ABIN2775888)

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAND1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CAND1 Antibody

Binding Specificity: N-Term

Sequence: TVIGELPPAS SGSALAANVC KKITGRLTSA IAKQEDVSVQ LEALDIMADM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TIP120A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TIP120A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAND1

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Alternative Name: TIP120A

Background: TIP120A functions as a negative regulator of SCF E3 ubiquitin ligases and may modulate other cullin ligases in a similar fashion.
Alias Symbols: TIP120, TIP120A
Protein Interaction Partner: ISG15, SUMO2, SUMO3, UBE2D1, UBC, UBE2M, CUL1, ASB2, ASB1, PPM1G, PAWR, OSBP, KARS, GARS, CARS, APEH, STAT1, SHMT2, IPO7, SEC23A, JMJD6, HSPA4, TRMT112, ZYX, DCUN1D5, DCUN1D1, SRPK2, UBD, FBXL3, FN1, CFTR, vif, CA9, ECT2, NOTCH1, CUL4A, CUL5, RBX1, ERCC6,
Protein Size: 1230

Molecular Weight: 136 kDa

Gene ID: 55832

NCBI Accession: NM_018448, NP_060918

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization