OTUD7B antibody (Middle Region)

Catalog No. ABIN2775897

The Rabbit Polyclonal anti-OTUD7B antibody has been validated for WB and IHC. It is suitable to detect OTUD7B in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for OTUD7B antibody (Middle Region) (ABIN2775897)

Target: OTUD7B (OTU Domain Containing 7B (OTUD7B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTUD7B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-OTUD7B Antibody

Binding Specificity: Middle Region

Sequence: VGTLKMGHRH QYQEEMIQRY LSDAEERFLA EQKQKEAERK IMNGGIGGGP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against OTUD7B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OTUD7B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 843 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OTUD7B

Target: OTUD7B (OTU Domain Containing 7B (OTUD7B))

Alternative Name: OTUD7B

Background: The ZA20D1 (OTUD7B) gene encodes an enzyme that cleaves ubiquitin from proteins. This gene has the ability to down-regulate NF-kappa B which plays a pivotal role in inflammatory processes through induction of adhesion molecules and chemokines.
Alias Symbols: CEZANNE, ZA20D1
Protein Interaction Partner: UBC, LGR4, WWOX, MSH3, XPO1, UBE2S, EGFR, PARK7, HIF1AN, ACAD9, NUP155, SLC9A3R2, UBB, TRAF6,
Protein Size: 843

Molecular Weight: 92 kDa

Gene ID: 56957

NCBI Accession: NM_020205, NP_064590

UniProt: Q6GQQ9