UHRF2 antibody (Middle Region)

Catalog No. ABIN2775913

The Rabbit Polyclonal anti-UHRF2 antibody (ABIN2775913) specifically detects UHRF2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for UHRF2 antibody (Middle Region) (ABIN2775913)

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UHRF2 Antibody

Binding Specificity: Middle Region

Sequence: NCDAPLDDKI GAESRNWRAG KPVRVIRSFK GRKISKYAPE EGNRYDGIYK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against UHRF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UHRF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 802 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UHRF2

Target: UHRF2 (Ubiquitin-Like with PHD and Ring Finger Domains 2, E3 Ubiquitin Protein Ligase (UHRF2))

Alternative Name: UHRF2

Background: UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.
Alias Symbols: DKFZp434B0920, DKFZp686G0837, MGC33463, NIRF, RNF107, RP11-472F14.2, URF2
Protein Interaction Partner: UBE2D1, UBC, TP53, UHRF2, TRIM27, E2F1, MPG, SMAD4, ZNF131, SUMO1, UBE2I, ATXN1, USP7, TWF2, TRIM8, RBCK1, TFAP4, PCNP, CDK2, CCNE1, UHRF1, EHMT2, HIST1H3A, SUMO2, DNMT3B, DNMT3A, DNMT1, CDK1, CD27, CCNB1, CCNA2, BCL2L1, CCND1, BAX, BCAR1, YY1, SKP1, RB1,
Protein Size: 802

Molecular Weight: 90 kDa

Gene ID: 115426

NCBI Accession: NM_152896, NP_690856

UniProt: Q96PU4