KCNIP4 antibody (N-Term)

Catalog No. ABIN2775914

This Rabbit Polyclonal antibody specifically detects KCNIP4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit and Dog.

Quick Overview for KCNIP4 antibody (N-Term) (ABIN2775914)

Target: KCNIP4 (Kv Channel Interacting Protein 4 (KCNIP4))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNIP4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNIP4 Antibody

Binding Specificity: N-Term

Sequence: NVRRVESISA QLEEASSTGG FLYAQNSTKR SIKERLMKLL PCSAAKTSSP

Predicted Reactivity: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against KCNIP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 250 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNIP4

Target: KCNIP4 (Kv Channel Interacting Protein 4 (KCNIP4))

Alternative Name: KCNIP4

Background: KCNIP4 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: CALP, KCHIP4, MGC44947
Protein Interaction Partner: APP, KCND2, PSEN2, PSEN1, KCNIP2,
Protein Size: 250

Molecular Weight: 29 kDa

Gene ID: 80333

NCBI Accession: NM_025221, NP_079497

UniProt: Q6PIL6