TRIM8 antibody (Middle Region)

Catalog No. ABIN2775917

This Rabbit Polyclonal antibody specifically detects TRIM8 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Pig and Guinea Pig.

Quick Overview for TRIM8 antibody (Middle Region) (ABIN2775917)

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Reactivity: Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM8 Antibody

Binding Specificity: Middle Region

Sequence: QSVPLYPCGV SSSGAEKRKH STAFPEASFL ETSSGPVGGQ YGAAGTASGE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRIM8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 551 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM8

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Alternative Name: TRIM8

Background: This protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
Alias Symbols: GERP, RNF27
Protein Interaction Partner: BRAP, TRIM25, PCGF5, MSL2, RNF141, TRIM2, USP7, TP53, CCNH, OTUB2, USP21, USP39, USP2, TNFAIP3, UBE2D2, TRIM47, TRIM15, TRIM8, RAD18, TRIM39, RNF111, RC3H2, RNF138, RNF181, RCHY1, RNF41, TRIM43, UHRF2, TRIM9, RNF7, TRIM24, RNF113A, MKRN3, TRAF5, TRIM21, S
Protein Size: 551

Molecular Weight: 61 kDa

Gene ID: 81603

NCBI Accession: NM_030912, NP_112174

UniProt: Q9BZR9