PSIP1 antibody (Middle Region)

Catalog No. ABIN2775929

This Rabbit Polyclonal antibody specifically detects PSIP1 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Dog, Horse, Guinea Pig, Cow, Rabbit and Sheep.

Quick Overview for PSIP1 antibody (Middle Region) (ABIN2775929)

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Reactivity: Human, Rat, Mouse, Dog, Horse, Guinea Pig, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PSIP1 Antibody

Binding Specificity: Middle Region

Sequence: AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against PSIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1

Background: PSIP1 is a transcriptional coactivator. It also acts as an adaptor to coordinate pre-mRNA splicing and transcriptional activation of class II genes.
Alias Symbols: p52, p75, PAIP, DFS70, LEDGF, PSIP2
Protein Interaction Partner: PPP2R1A, UBC, RPA3, RPA2, RPA1, HMGA2, HMGA1, WHSC1, CSNK2A1, gag-pol, ESR1, ZC3H18, FTSJ3, EXOSC5, EXOSC4, NCSTN, RRS1, SUPT16H, SAP18, THRAP3, EIF4A3, U2AF1, TPBG, SON, TRA2B, RPS24, RPS11, RPL6, CAST, SH3KBP1, MEN1, SUMO1, SUMO2, HDGF, MAPK6, KMT2A, BA
Protein Size: 530

Molecular Weight: 60 kDa

Gene ID: 11168

NCBI Accession: NM_033222, NP_150091

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization