TRIM6 antibody (Middle Region)

Catalog No. ABIN501320

The Rabbit Polyclonal anti-TRIM6 antibody is suitable to detect TRIM6 in samples from Human, Rat, Mouse, Rabbit, Cow, Horse, Dog, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for TRIM6 antibody (Middle Region) (ABIN501320)

Target: TRIM6 (Tripartite Motif Containing 6 (TRIM6))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Horse, Dog, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM6 Antibody

Binding Specificity: Middle Region

Purpose: TRIM6 Antibody - middle region

Sequence: FNQLRNILDR VEQRELKKLE QEEKKGLRII EEAENDLVHQ TQSLRELISD

Predicted Reactivity: Cow: 86%, Dog: 90%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 90%, Rabbit: 90%, Rat: 90%, Yeast: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against TRIM6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34655-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM6

Target: TRIM6 (Tripartite Motif Containing 6 (TRIM6))

Alternative Name: TRIM6

Background:

Background Information: TRIM6 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A read-through transcript transcribed from this gene and TRIM34 has been observed.

Gene Name: Tripartite motif containing 6

Alternative Symbols: RNF89

Protein Name: Tripartite motif-containing protein 6

Molecular Weight: 56kDa

Gene ID: 117854

NCBI Accession: NP_001003818

UniProt: A8K2A7