MEIS2 antibody (N-Term)
Quick Overview for MEIS2 antibody (N-Term) (ABIN2775951)
Target
See all MEIS2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- HYGAHAPHPN VMPASMGSAV NDALKRDKDA IYGHPLFPLL ALVFEKCELA
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Specificity
- This antibody will recognize both MEIS1 and MEIS2 isoforms
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Characteristics
- This is a rabbit polyclonal antibody against MEIS2. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MEIS2
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 477 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier." in: Journal of cell science, Vol. 124, Issue Pt 10, pp. 1681-90, (2011) (PubMed).
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: "TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier." in: Journal of cell science, Vol. 124, Issue Pt 10, pp. 1681-90, (2011) (PubMed).
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- MEIS2 (Meis Homeobox 2 (MEIS2))
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Alternative Name
- MEIS2
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Background
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MEIS2 encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs.
Alias Symbols: MRG1, HsT18361
Protein Interaction Partner: LINC00238, C1orf94, OSGIN1, MEIS2, ANXA1, CRBN, ARNT2, DGCR6, SQSTM1, SOX2, APP, SP1, PBX1, ZNHIT3, TRIM25, HOXA13, HOXA9,
Protein Size: 477 -
Molecular Weight
- 52 kDa
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Gene ID
- 4212
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NCBI Accession
- NM_170675, NP_733775
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UniProt
- O14770
Target
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