TRIM3 antibody (N-Term)

Catalog No. ABIN2775959

The Rabbit Polyclonal anti-TRIM3 antibody is suitable to detect TRIM3 in samples from Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for TRIM3 antibody (N-Term) (ABIN2775959)

Target: TRIM3 (Tripartite Motif Containing 3 (TRIM3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIM3 Antibody

Binding Specificity: N-Term

Purpose: TRIM3 Antibody - N-terminal region

Sequence: TICGAKQKVL QSQLDTLRQG QEHIGSSCSF AEQALRLGSA PEVLLVRKHM

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against TRIM3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114661

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM3

Target: TRIM3 (Tripartite Motif Containing 3 (TRIM3))

Alternative Name: TRIM3

Background:

Background Information: The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport.

Gene Name: Tripartite motif containing 3

Alternative Symbols: BERP, HAC1, RNF22, RNF97

Protein Name: cDNA FLJ44731 fis, clone BRACE3025719, highly similar to Homo sapiens ring finger protein 22 (RNF22) EMBL BAC86643.1

Molecular Weight: 81kDa

Gene ID: 10612

NCBI Accession: NP_006449

UniProt: Q6ZTE7