PSIP1 antibody (N-Term)

Catalog No. ABIN2775996

This Rabbit Polyclonal antibody specifically detects PSIP1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Horse, Guinea Pig, Cow, Rabbit, Sheep and Pig.

Quick Overview for PSIP1 antibody (N-Term) (ABIN2775996)

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Reactivity: Human, Rat, Mouse, Dog, Horse, Guinea Pig, Cow, Rabbit, Sheep, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSIP1 Antibody

Binding Specificity: N-Term

Sequence: DNNPKVKFSS QQAATKQSNA SSDVEVEEKE TSVSKEDTDH EEKASNEDVT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against PSIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PSIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 333 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1

Background: PSIP1 encodes a multidomain adaptor protein that interacts with the nuclear import apparatus, lentiviral IN proteins and chromatin by means of an NLS, an IBD and additional chromatin-interacting domains.
Alias Symbols: DFS70, LEDGF, MGC74712, PAIP, PSIP2, p52, p75
Protein Interaction Partner: PPP2R1A, UBC, RPA3, RPA2, RPA1, HMGA2, HMGA1, WHSC1, CSNK2A1, gag-pol, ESR1, ZC3H18, FTSJ3, EXOSC5, EXOSC4, NCSTN, RRS1, SUPT16H, SAP18, THRAP3, EIF4A3, U2AF1, TPBG, SON, TRA2B, RPS24, RPS11, RPL6, CAST, SH3KBP1, MEN1, SUMO1, SUMO2, HDGF, MAPK6, KMT2A, BA
Protein Size: 333

Molecular Weight: 38 kDa

Gene ID: 11168

NCBI Accession: NM_021144, NP_066967

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization