TRIM39 antibody (Middle Region)

Catalog No. ABIN2775998

There is 1 publication for this product available. The Rabbit Polyclonal anti-TRIM39 antibody is suitable to detect TRIM39 in samples from Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig and Horse. It has been validated for WB and IHC.

Quick Overview for TRIM39 antibody (Middle Region) (ABIN2775998)

Target: TRIM39 (Tripartite Motif Containing 39 (TRIM39))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM39 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIM39 Antibody

Binding Specificity: Middle Region

Purpose: TRIM39 Antibody - middle region

Sequence: GELKRLVESR RQQILREFEE LHRRLDEEQQ VLLSRLEEEE QDILQRLREN

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TRIM39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM39

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34756-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRIM39 antibody (ABIN2775998)

Roberts, Chiche, Kolpa, Bloch, Bloch: "cGMP-dependent protein kinase I interacts with TRIM39R, a novel Rpp21 domain-containing TRIM protein." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 293, Issue 4, pp. L903-12, (2007) (PubMed).

Target Details for TRIM39

Target: TRIM39 (Tripartite Motif Containing 39 (TRIM39))

Alternative Name: TRIM39

Background:

Background Information: The protein encoded by TRIM39 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms.

Gene Name: Tripartite motif containing 39

Alternative Symbols: TFP, RNF23, TRIM39B

Protein Name: E3 ubiquitin-protein ligase TRIM39

Molecular Weight: 60kDa

Gene ID: 56658

NCBI Accession: NP_067076

UniProt: Q9HCM9