TRIM69 antibody (N-Term)

Catalog No. ABIN2776005

This Rabbit Polyclonal antibody specifically detects TRIM69 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Pig, Rabbit and Dog.

Quick Overview for TRIM69 antibody (N-Term) (ABIN2776005)

Target: TRIM69 (Tripartite Motif Containing 69 (TRIM69))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM69 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM69 Antibody

Binding Specificity: N-Term

Purpose: TRIM69 Antibody - N-terminal region

Sequence: NKLHLQQHVS MEFLKLHQFL HSKEKDILTE LREEGKALNE EMELNLSQLQ

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against TRIM69. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM69

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34764-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM69

Target: TRIM69 (Tripartite Motif Containing 69 (TRIM69))

Alternative Name: TRIM69

Background:

Background Information: TRIM69 is a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis.This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name: Tripartite motif containing 69

Alternative Symbols: Trif, HSD34, RNF36, HSD-34

Protein Name: Tripartite motif-containing protein 69

Molecular Weight: 39kDa

Gene ID: 140691

NCBI Accession: NP_542783

UniProt: Q86WT6