THRA antibody (C-Term)

Catalog No. ABIN2776018

The Rabbit Polyclonal anti-THRA antibody has been validated for WB. It is suitable to detect THRA in samples from Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for THRA antibody (C-Term) (ABIN2776018)

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THRA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-THRA Antibody

Binding Specificity: C-Term

Sequence: MSTDRSGLLC VDKIEKSQEA YLLAFEHYVN HRKHNIPHFW PKLLMKVTDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Thra. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 492 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for THRA

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Alternative Name: Thra

Background: Thra binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation.
Alias Symbols: ERBA1, Thra1
Protein Interaction Partner: Pik3r1,
Protein Size: 492

Molecular Weight: 55 kDa

Gene ID: 81812

NCBI Accession: NM_001017960, NP_001017960

UniProt: P63059

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development