MED23 antibody (N-Term)

Catalog No. ABIN2776066

This Rabbit Polyclonal antibody specifically detects MED23 in WB. It exhibits reactivity toward Human, Rat, Mouse, Horse, Rabbit, Dog, Cow, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for MED23 antibody (N-Term) (ABIN2776066)

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Dog, Cow, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED23 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MED23 Antibody

Binding Specificity: N-Term

Sequence: METQLQSIFE EVVKTEVIEE AFPGMFMDTP EDEKTKLISC LGAFRQFWGG

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against MED23. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MED23

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1368 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MED23

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Alternative Name: MED23

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. T
Alias Symbols: CRSP130, CRSP133, CRSP3, DKFZp434H0117, DRIP130, SUR2, MRT18, SUR-2, ARC130
Protein Interaction Partner: UBC, ELF3, CDK19, CDK8, MED6, MED19, MED26, FBXW7, EPAS1, NOTCH1, PDXP, UBD, COPS2, UL48, NIPBL, ELAVL1, CTDP1, SREBF1, MED25, MED15, MED14, VDR, MED1, BCL6, MED28, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, RELA, TRRAP, ETS1, PARP1, MED30, EHMT2, M
Protein Size: 1368

Molecular Weight: 156 kDa

Gene ID: 9439

NCBI Accession: NM_004830, NP_004821

UniProt: Q9ULK4

Pathways: Regulation of Lipid Metabolism by PPARalpha