KCNN4 antibody (C-Term)
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- Target See all KCNN4 Antibodies
- KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Cow, Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNN4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DLQQNLSSSH RALEKQIDTL AGKLDALTEL LSTALGPRQL PEPSQQSK
- Predicted Reactivity
- Cow: 92%, Horse: 92%, Human: 100%, Pig: 83%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against KCNN4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN4
- Top Product
- Discover our top product KCNN4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 427 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KCNN4 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))
- Alternative Name
- KCNN4 (KCNN4 Products)
- Synonyms
- KCa3.1 antibody, IK1 antibody, IKCA1 antibody, KCA4 antibody, SK4 antibody, hIKCa1 antibody, hKCa4 antibody, hSK4 antibody, rKCNN4c antibody, rSK4 antibody, SKCas antibody, mIKCa1 antibody, potassium calcium-activated channel subfamily N member 4 antibody, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 antibody, KCNN4 antibody, Kcnn4 antibody
- Background
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KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4
Protein Interaction Partner: UBC, RAB7A, TSG101, Cam, CALM1, USP8, PRKAG1,
Protein Size: 427 - Molecular Weight
- 48 kDa
- Gene ID
- 3783
- NCBI Accession
- NM_002250, NP_002241
- UniProt
- O15554
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