TRPC7 antibody (C-Term)

Catalog No. ABIN2776232

The Rabbit Polyclonal anti-TRPC7 antibody is suitable to detect TRPC7 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for TRPC7 antibody (C-Term) (ABIN2776232)

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRPC7 Antibody

Binding Specificity: C-Term

Sequence: KAQVDRENDE VNEGELKEIK QDISSLRYEL LEEKSQATGE LADLIQQLSE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TRPC7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TRPC7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRPC7

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Alternative Name: TRPC7

Background: TRPC7 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC7 probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) and may also be activated by intracellular calcium store depletion.
Alias Symbols: TRP7
Protein Interaction Partner: MX1, ITPR3, TRPC7, TRPC6, TRPC3,
Protein Size: 862

Molecular Weight: 99 kDa

Gene ID: 57113

NCBI Accession: NM_020389, NP_065122

UniProt: Q9HCX4