KCNK13 antibody (C-Term)

Catalog No. ABIN2776250

Product Details anti-KCNK13 Antibody

Target: KCNK13 (Potassium Channel Subfamily K Member 13 (KCNK13))

Binding Specificity: C-Term

Reactivity: Human, Rat, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GEMISMKDLL AANKASLAIL QKQLSEMANG CPHQTSTLAR DNEFSGGVGA

Predicted Reactivity: Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against KCNK13. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KCNK13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 408 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KCNK13 antibody (ABIN2776250)

Sakamaki, Ishii, Sakata, Takemoto, Takagi, Takeuchi, Morishita, Takahashi, Nozawa, Shinoda, Chiba, Sugimoto, Saito, Tamate, Satou, Jung, Matsuoka, Koyamada, Sawasaki, Nagai, Ueno: "Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage." in: Biochimica et biophysica acta, Vol. 1863, Issue 11, pp. 2766-2783, (2016) (PubMed).

Target Details for KCNK13

Target: KCNK13 (Potassium Channel Subfamily K Member 13 (KCNK13))

Alternative Name: KCNK13 (KCNK13 Products)

Synonyms: BB085247 antibody, F730021E22Rik antibody, Gm1570 antibody, Gm1685 antibody, K2p13.1 antibody, THIK-1 antibody, THIK1 antibody, prdx1 antibody, kcnk13 antibody, si:ch211-173b9.3 antibody, zgc:171694 antibody, potassium channel, subfamily K, member 13 antibody, potassium two pore domain channel subfamily K member 13 antibody, potassium channel subfamily K member 13 antibody, potassium channel, subfamily K, member 13b antibody, potassium channel, subfamily K, member 13a antibody, Kcnk13 antibody, KCNK13 antibody, Tsp_07890 antibody, kcnk13b antibody, kcnk13a antibody

Background: KCNK13 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming domains. The product of this gene is an open channel that can be stimulated by arachidonic acid.
Alias Symbols: THIK1, THIK-1, K2p13.1
Protein Size: 408

Molecular Weight: 45 kDa

Gene ID: 56659

NCBI Accession: NM_022054, NP_071337

UniProt: Q9HB14