KCTD12 antibody (C-Term)

Catalog No. ABIN2776278

This Rabbit Polyclonal antibody specifically detects KCTD12 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for KCTD12 antibody (C-Term) (ABIN2776278)

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCTD12 Antibody

Binding Specificity: C-Term

Sequence: PDRPPERYTS RYYLKFNFLE QAFDKLSESG FHMVACSSTG TCAFASSTDQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Kctd12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Kctd12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCTD12

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Alternative Name: Kctd12

Background: Kctd12 is an auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. It increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Alias Symbols: AU046135, AW538430, Pfet1, Pfetin
Protein Size: 327

Molecular Weight: 35 kDa

Gene ID: 239217

NCBI Accession: NM_177715, NP_808383

UniProt: Q6WVG3

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling