KCNH7 antibody (N-Term)

Catalog No. ABIN2776316

The Rabbit Polyclonal anti-KCNH7 antibody is suitable to detect KCNH7 in samples from Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit and Cow. It has been validated for WB.

Quick Overview for KCNH7 antibody (N-Term) (ABIN2776316)

Target: KCNH7 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 7 (KCNH7))

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNH7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNH7 Antibody

Binding Specificity: N-Term

Purpose: KCNH7 Antibody - N-terminal region

Sequence: PILPIKTVNR KFFGFKFPGL RVLTYRKQSL PQEDPDVVVI DSSKHSDDSV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KCNH7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNH7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108733

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNH7

Target: KCNH7 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 7 (KCNH7))

Alternative Name: KCNH7

Background:

Background Information: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH7 is a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.

Gene Name: Potassium voltage-gated channel, subfamily H (eag-related), member 7

Alternative Symbols: ERG3, HERG3, Kv11.3

Protein Name: Potassium voltage-gated channel subfamily H member 7

Molecular Weight: 83kDa

Gene ID: 90134

NCBI Accession: NP_775185

UniProt: Q8IV15