GABRG2 antibody (C-Term)

Catalog No. ABIN2776351

The Rabbit Polyclonal anti-GABRG2 antibody (ABIN2776351) specifically detects GABRG2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for GABRG2 antibody (C-Term) (ABIN2776351)

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRG2 Antibody

Binding Specificity: C-Term

Purpose: GABRG2 Antibody - C-terminal region

Sequence: AMDLFVSVCF IFVFSALVEY GTLHYFVSNR KPSKDKDKKK KNPAPTIDIR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GABRG2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABRG2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101280

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRG2

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Alternative Name: GABRG2

Background:

Targeted Subunit: gamma-2

Background Information: Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. GABRG2 is the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. This gene encodes the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.

Gene Name: Gamma-aminobutyric acid (GABA) A receptor, gamma 2

Alternative Symbols: CAE2, ECA2, FEB8, DEE74, EIEE74, GEFSP3

Protein Name: Gamma-aminobutyric acid receptor subunit gamma-2

Molecular Weight: 36kDa

Gene ID: 2566

NCBI Accession: NP_944493

UniProt: P18507